Fertility Portfolio

Addressing the biology upstream of fertility and pregnancy outcomes.

Our portfolio tests both partners for the genetic variants that affect how they metabolize and utilize one-carbon nutrients — an assessment standard fertility workups currently do not include.

The portfolio

Commercially available

Genate — Prenatal and Preconception

A precision nutrition genetic test evaluating five interdependent metabolic pathways and returning individualized nutritional guidance.

Explore Genate In development

Sperm Function — Male Fertility

A genetic test and nutritional approach addressing the choline metabolism that sperm mitochondrial function depends on. US Patent issued for test and nutritional intervention.

Explore Sperm Function In development

Fetal Alcohol Spectrum Disorders

The portfolio's next extension. The same pathways that shape fertility and early development also determine which children respond to choline following prenatal alcohol exposure.

See the pipeline

One-carbon nutrition — choline, betaine, folate

Genate in female fertility

Critical for optimal reproductive health, from egg development through fetal brain growth.

  • Supports fertility and cellular competence.

    Provides the nutritional foundation needed for healthy egg development, fertilization, and early embryo viability.

  • Builds new cells.

    Fuels the rapid cell growth required during early embryogenesis and pregnancy.

  • Programs healthy development.

    Supports the genetic and epigenetic processes that guide development from conception onward.

  • Powers growth.

    Provides nutrients needed for cellular energy production in eggs, embryos, and the placenta.

  • Builds the developing brain.

    Supplies key structural nutrients required for fetal brain and nervous system development.

Why this matters

Common, and unknown without testing

Reproductive outcomes depend on metabolic processes that nutrient availability constrains: methylation capacity, membrane formation, and mitochondrial function. Genetic variation determines how efficiently an individual can manage these processes and therefore how much of each nutrient they require.

  • 78%

    of women carried homozygous variants in at least one sub-pathway

  • 38%

    carried variants across multiple sub-pathways

These genetic challenges impacting reproductive health are common, and they are “unknown” without testing.

For clinics and practices

Where this fits in your protocols

  • A precision nutrition layer, not a replacement.

    Genate complements established fertility protocols. It addresses cellular competence upstream of the interventions a practice already runs.

  • Reference intakes describe a population, not a patient.

    A woman whose variants constrain a pathway has a different requirement for the nutrients feeding it than the general guidance assumes. Genate identifies the pathway and her requirement.

  • Inside your workflow.

    Samples are processed in a CLIA-CAP certified laboratory. SNPhub™ returns a HIPAA-compliant report.

For patients

If you are planning a pregnancy or being seen for fertility, Genate identifies the metabolic pathways where your own genetics change what you need nutritionally — before conception, when that information is most useful.

Learn more